There was an article in Vox a few days ago which made a fairly persuasive case that the GOP’s efforts to completely repeal Obamacare should be over, at least for the next year or so. This was partly due to the Jones victory, but it was also the result of the repeal of the individual mandate in the tax bill. The thinking was that the mandate was the least popular feature of Obamacare, so with it gone, the GOP will find it much more difficult to rally support to get rid of the rest of the program.
The other side of the coin, which was not discussed in the article, is that the repeal of the mandate also complicates things for the Democrats. It would be very difficult to sell the public on a bill that simply reimposes the mandate; that would be vegetables without dessert. There are two likely outcomes: either the Democrats will simply accept the structure of the system as it is, and simply try to make it work better with an infusion of more public money; or they will push harder for single-payer. I think you will hear both options discussed, but the latter will predominate.
The GOP has made it easier to imagine single-payer becoming law in spite of widespread opposition; you simply keep the bill a secret until the last minute, jam it through the system as fast as possible, and make shady deals to keep everyone on board. As ye sow, so shall ye reap.