If the Iranian regime gave any sort of a crap about the material well-being of its subjects, it would give up its nukes and sign a big, beautiful deal with Trump for sanctions relief. It doesn’t, and it won’t. Why?
Because the ayatollahs at the top of the food chain think their system is ordained by God; it is his will, not the material desires of the people, that must prevail, even in the face of calamity. And because the more prosaic interests of the instruments of repression–most notably, the Revolutionary Guards–are completely entwined with the current system; the Guards would be risking their power and privileges if they supported regime change.
As long as these two groups of people are united in their desire to maintain the status quo, there is no realistic hope of reform in Iran. If the regime splits, however, it is doomed, because it doesn’t have any public support. That probably won’t happen until Khamenei dies, which can’t happen soon enough.